MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

The puzzle seems impossible: take a three-billion-letter code and predict what happens if you swap a single letter. The code we’re talking about—the human genome—stores most of its instructions in ...

Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...

Many cancers harbor pro-proliferative mutations of the mitogen-activated protein kinase (MAPK) pathway. In BRAF-driven melanoma cells treated with BRAF inhibitors, subpopulations of cells escape ...

While CRISPR is probably the most prominent gene-editing technology, there are others, some developed before and since. And people have been developing CRISPR variants to perform more specialized ...

R-loops are structures that form when a strand of RNA (red) forms a stable structure with double-stranded DNA, causing one strand of the DNA to form a loop. R-loops are associated with gene ...

Future data centers might do away with banks of hard drives and switch to a storage medium that nature has been using for billions of years – DNA. In a major step towards making that a reality, ...

Here's a scenario: police take a blood sample from a crime scene. They compare the DNA to that of convicted criminals, but get no match. But they find someone with similar DNA, and that leads them to ...