An international team, including researchers from HSE University, has created the first comprehensive map of ...

DNA sequences that regulate expression of the insulin gene are located within a region spanning ~400 bp that flank the transcription start site. This region, the insulin promoter, contains a number of ...

A recent study in genetic control elements revealed around 11,000 gene regulators active in every cell type, also known as housekeeping cis-regulatory elements (HK-CREs). These elements are vital in ...

Around 98.5% of human DNA is non-coding, meaning it doesn’t get copied to make proteins. A new study has connected many of these non-coding regions to the genes they affect and laid out guidelines for ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...

This study identifies around 11,000 housekeeping cis-regulatory elements (HK-CREs), revealing their important role in cellular stability and potential tumor suppression capability across diverse ...