Fluidized bed spray granulation is a versatile process that integrates the controlled spraying of a binder liquid onto fluidized particles, leading to the formation of agglomerates or granules with ...

Formulating drugs to ensure therapeutic consistency, enable rapid development, and allow for cost-effective scale-up has become increasingly challenging. This is especially true in the context of ...

Spatial filter techniques, along with delivering real-time particle size measurement, offer several further attractions such as simple hardware requirements, ease of use and reasonable commercial cost ...

The pharmaceutical manufacturing platforms of fluid-bed granulation and milling are widely used to modify particle size. However, the adoption of process analytical technology to monitor and control ...

Using a specific addition method to wet the powder bed in twin-screw granulation using a foam binder improves robustness for continuous solid-dosage drug product manufacturing. In less than a decade, ...

Iron ore granulation and sintering technology encompasses the processes that transform fine iron ore particles into coherent multicomponent agglomerates suitable for use in blast furnaces. Granulation ...

Pharmaceutical manufacturing practices are advancing towards a future in which continuous manufacturing processes will be the norm. Developing and applying such techniques is therefore an essential ...

In dry granulation, powders bind because of the application of mechanical stress. As particles are forced to be within closer proximity, entrained air is forced out, bulk density increases, and a ...

The last decade has seen an impressive growth in the research and mechanistic understanding of the agglomeration process, along with attempts to model the process. There have even been a few papers on ...