The X-ray repair cross-complementing group 3 (XRCC3), one of the DNA repair genes, codes for a protein participating in homologous recombination repair (HRR) of DNA double-strand breaks (DSB). It is a ...

In this issue, Gryshchenko et al 1 report that a known single nucleotide polymorphism (SNP) in the promoter region of MDM2 is associated with treatment-free and overall survival in chronic lymphocytic ...

Several reports have found a relation between polymorphisms of the vitamin D receptor gene (VDR) and the development of type 1 diabetes. We have examined the ...

In a recent study posted to the medRxiv* pre-print server, researchers reported the association of a single nucleotide polymorphism (SNP) rs9984273 in the interferon-alpha/beta receptor (IFNAR2) gene ...

Biomarker Analyses and Final Overall Survival Results From a Phase III, Randomized, Open-Label, First-Line Study of Gefitinib Versus Carboplatin/Paclitaxel in ...

Traditionally, chromosome polymorphisms have been considered normal variants without clinical significance. However, the study is the first to find a significantly higher prevalence of chromosome ...

Background: The measles virus (MV) interacts with two known cellular receptors: CD46 and SLAM. The transmembrane receptor CD209 interacts with MV and augments dendritic cell infection. Methods: 764 ...

1982 The Human Polymorphism Study Center, the first academic institution to propose the systematic study of polymorphisms, is founded in Paris. Its primary objective: to make an inventory of all ...

This new study, which will appear in the June 2005 issue of The American Naturalist, asserts that an individual could use his/her genotype as an informative cue when "deciding" which phenotype ...

Your genetic makeup can help determine how well your body will respond to weight loss efforts aimed at controlling high blood pressure, a new study confirms. Your genetic makeup can help determine how ...